The study included 40 cases of bone metastasis experienced from January 1982 to August 1986 at the Department of Radiology, Okayama University Hospital. The rate of pain Remission was 89.6% in 29 patients given radiotherapy. Increases in serum ALP and LDH were found in a few patients and a quarter of these patients improved after radiotherapy. Serum Ca increased in 5 patients with multiple bone metastases.