Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

癌の腹膜播種の成立機序に関する実験的研究

Okabayashi, Hiroki
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Abstract
The electron microscopic study of the mechanism of the implantation of the tumor cells to the peritoneum has been investigated through the rats. The experiment was made with the inoculation of Walker 256 tumor cells into their abdominal cavity. The morphalogic change and the detouching cell contact of the mesothelium make up the phenomenon, leaving empty spaces to basement membrane. This phenomenon makes it easy that the tumor cell contact with the basement membrane. This contacted tumor cell protrudes the pseudopods and begin subserosal invasion, with moving the intracellular organelles. Stretching the pseudopod, the tumor cell invades the subserosal layer, and the implantation is performed.
ISSN
0030-1558
NCID
AN00032489