Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

線維芽細胞抑制剤による悪性腫瘍の治療に関する研究 第3編 クロロキンの担腫瘍動物(Ehrlich腹水癌, MH134腹水肝癌)に及ぼす影響

Shibuya, Koichi
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Effects of fibroblast-inhibiting chloroquine diphosphate on ascites tumors such as Ehrlich ascites carcinoma and MH 134 ascites hepatoma weres tudied and the following results were obtained. 1) The survival of animals with Ehrlich ascites carcinoma was not prolonged but the tumor cells in the ascites tended to show a silght decrase. 2) The subcutaneous nodules of Ehrlich carcinoma and MH 134 hepatoma were not inhibited nor were the life span of tumor-bearing animals prolonged. 3) Implantantation of Ehrlich ascites carcinoma cells in vitro treated with the drug showed no difference from control.