Basic Studies on Metastatic Activity of Malignant TumorsPart Ⅱ. A Study on TAME-Lysis and Caseinolysis in the Malignant Tumors and the Host Tissues

TAEM-lysis and caseinolysis are stronger in any carcinoma than in none-carcinomatous mucous membrane of the stomach. And those lytic activities, which are generally activated by malignant change such as carcinomas in alimentary tract, breast and thyroid, are marked in epithelial tissue in comparison with none-epithelial tissue and brain tissue. This lytic substance might be plasmin or protease-like substance, because it is not activated by strepto-kinase. This result presumably shows a certain relation among the proteolytic activity, metastatic ability and primary tissue of the tumors.