Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

Ehrlich腹水癌移植腫瘍の局所リンパ節に存在する抗腫瘍性に関する研究 第2編 DEAE Sephadex A-50カラムクロマトグラフィーによる抗腫瘍性蛋白質の分離,精製

Okano, Yutaka
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The supernatant of the regional lymph node of mice transplanted with Ehrlich ascites tumor were fractionated on DEAE Sephadex A-50 column chromatography with linear gradient elution. The eluted peaks were examined electrophretically. They were γ, β. α and albumin. β and α fractions were effective for suppression of Ehrlich ascites cell growth. Minimum effective β fraction was 300μg/ml. The sedimentation coefficient of β fraction was 6.5 S 20 w, and that of α fraction was 7.4 S 20 w.