Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

麻醉法並に手術操作の脳含水量に及ぼす影響に関する実験的研究 第1編 各種麻醉法の脳含水量に及ぼす影響に関する実験的研究

Sunami, Toshihiko
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1) The ether inhalation, intramuscular injection of dial, rectal infusion of avertin, intravenous injection of ravonal, subcutaneous injection of narcopon and scopolamin and local injection of procaine chloride were performed in cats. From their clinical and electroencephalographic findings, the state of narcosis was classified into 6 phases and the dose was determined to keep the 4th phase of narcosis. 2) Three hours after the narcosis of the 4th phase the amount of water in the brain was measured at the cortex, white substance, cerebellum and pons, dividing in free and bound water. 3) The amount of bound water showed no change in all cases. 4) The amount of free and total water was not influenced by narcosis with ravonal, dial and procaine, but increased by ether, avertin, and narcopon-scopolamin. 5) The degree of increase was in the following order: white substance, cortex and cerebellum. The pons showed the least increase.