Journal of Okayama Medical Association
Published by Okayama Medical Association

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Electrophoretic Study on Spinal Fluid Protein in Infantile Disseaes

Fujiwara, Hiroshi
Sano, Eiji
66_2283.pdf 1.24 MB
Published Date
1954-11-30
Abstract
Spinal fluid from children with Guillain-Barrés syndrome, Japanese encephalitis, and cerebral palsy was concentrated by Ewerbeck's method. Spinal fluid of high protein content from children with hemorrhagic duritis was not concentrated. Protein fractions were analysed with Tiselius' electrophoretic apparatus. The following results were obtained. 1) Spinal fluid protein contained 4 fractions as in serum protein. Beside these V-fraction before albumin and τ-fraction between β-globulin and γ-globulin were noted. γ-globulin was less than in serum. 2) In one case of Guillain-Barrés syndrome, and in the convalescent period of Japanese encephalitis, remarkably steep and sharp τ-peaks were noted. The peak in the former reached 7.0% and that in the latter 16.8%. γ-globulin percentage was somewhat higher than in other cases. 3) In cerebral palsy, no special changes were noted. 4) In hemorrhagic duritis, no V- and τ-fraction were noted. Almost the same results as in serum protein fractions were obtained.
ISSN
0030-1558
NCID
AN00032489