Journal of Okayama Medical Association
Published by Okayama Medical Association

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エリスロポエチン投与による貧血改善と透析効率の変化に関する検討

Makino, Hirohumi
Nagake, Yoshio
Haramoto, Toshinori
Matsumoto, Mitsuhito
Haramatsu, Makoto
Mino, Yasuaki
Nishimura, Shigeaki
Taniai, Kazuhi
Kumagai, Isao
Komoto, Kiichi
Takehisa, Yoshiaki
Matsuura, Umeharu
Suga, Yoshihiko
Ota, Zensuke
Thumnail 106_253.pdf 289 KB
Abstract
The administration of recombinant human erythropoietin (EPO) has considerably improved renal anemia in benodialysis patients. However, there is a possibility that plasma flow will decrease and cause a reduction of hemodialysis effciency after the improvement of anemia. In the present study, we examined the influence of the improvement of anemia EPO administration on the efficiency of dialysis in 44 hemodialysis patients with renal anemia (21 males and 23 females ; mean age : 59.5±14.6 years). Epo was administered at a dose of 3,000 units three times a week and the duration of treatment was generally 12 weeks. EPO treatment significantly improved anemia. However, the blood urea nitrogen, creatinine, and uric acid levels before and after dialysis as well as the potassium and phosporus levels before dialysis showed no significant changes after the improvement of renal anemia. Accordingly. it is unnecessary to take any specific measures to improve the efficiency of dialysis after treating renal anemia with EPO.
Keywords
腎性貧血
エリスロポエチン
透析効率
Note
原著
ISSN
0030-1558
NCID
AN00032489