A case of periarteritis nodosa with advanced A-V block and ventricular tachycardia is reported. The patient was a 62-year-old man who was admitted to Ibara City Hospital because of leg pain and fever. Laboratory examinations and microscopic examination of biopsy sections of the soleus muscle revealed that he had periarteritis nodosa. His electro cardiogram (ECG) and chest X-ray films on admission were normal. Treatment with prednisolone resulted in relief of his complaints, and improved laboratory data. One year later the parient complained of fainting attacks, and an ECG indicated non-sustained ventricular tachycardia. Two months later, a I° A-V block with LBBB appeared, which progressed to complete A-V block within a month. Good results were achieved with ventricular pacing (VVI) in this patient.