ID 58275
JaLCDOI
FullText URL
Author
Thar Htet San Department of Pathology and Experimental Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Ota, Yoko Department of Pathology and Experimental Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Fushimi, Soichiro Department of Pathology, Himeji Red Cross Hospital
Fujisawa, Masayoshi Department of Pathology and Experimental Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ORCID
Yanai, Hiroyuki Department of Pathology, Okayama University Hospital
Toda, Hiroko Section of Diagnostic Pathology, Fukuyama Medical Association
Kunitomo, Tadayoshi Department of Pathology, Kurashiki Medical Center
Kodama, Keisuke Department of Gynecology, Kurashiki Medical Center
Matsukawa, Akihiro Department of Pathology and Experimental Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ORCID Kaken ID publons researchmap
Abstract
Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (~97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested.
Keywords
juvenile granulosa cell tumor
late recurrence
adult granulosa cell tumor
Amo Type
Case Report
Published Date
2020-04
Publication Title
Acta Medica Okayama
Volume
volume74
Issue
issue2
Publisher
Okayama University Medical School
Start Page
159
End Page
163
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2020 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT
NAID