ID 55649
Sort Key
4
Title Alternative
Alzheimer’s disease : Relationship between the Alzheimer’s disease and human microbiome
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Author
Fujii, Yusuke
Morita, Hidetoshi
Abstract
Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by memory and language disorder. The accumulation of senile plaques called β-amyloid and neurofibrillary tangles involving protein tau in the brains of AD patients have been considered as two hallmarks of AD. In AD, it is reported that accumulation of β-amyloid may be observed 25 years before onset, supporting early diagnosis and treatment by brain image analysis, because several techniques have recently been developed to detect β-amyloid and tau protein in brains of persons diagnosed with AD. AD patients are usually suffering from other diseases such as diabetes or periodontal disease, and there is accumulating data to show that these diseases associate with the human microbiome, such as gut and oral microbiota. In this report, the relation ship between AD and the human microbiome is reviewed.
Note
総説 (Review article)
Publication Title
Scientific Reports of the Faculty of Agriculture, Okayama University
Published Date
2018-02-01
Volume
volume107
Publisher
岡山大学農学部
Start Page
5
End Page
10
ISSN
2186-7755
Content Type
Departmental Bulletin Paper
OAI-PMH Set
岡山大学
language
日本語
File Version
publisher
Eprints Journal Name
srfa