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ID 42557
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Thumnail 69_1311.pdf 3.14 MB
Title Alternative
Studies on the Function of Reticuloendotherial System and Serum Protein Found in an Immuned Rabbit
Author
Honjo, I.
Itasaka, T.
Obayashi, S.
Abstract
We, by frequent injection of a cow's serum antigen into a rabbit, and examining such as the coefficient of congored, total protein density of anti-serum, changes in precipitin as well as changes that occurred to the fraction of serum protein, electrophoretically and at a certain lapse of time; and having taken an observation on their correlations, succeeded to arrive at the following results; 1. Both γ-Globulin as well as precipitin changes proved as parallel. The same tendency has been detected in β-Globulin, but not so marked as in the case of γ-Globulin. 2. A overfunction of reticuloendotherial action has been occurred, caused by immunology; in general, that sort of hyperbole can be seen from 10-30 days after the 1st injection of antigen. 3. The total protein density of serum-antigen has increased or decreased side by side with changes of precipitin, but changes in Albumin and Globulin have proved no such steadfast trend. 4. A markedly low case in precipitin formation has been discovered in a rabbit which possessed a very slight amount of γ-Globulin within normal serum, previous to antigeninjection. 5. From the above results, it was found that a close connection exists between those Globulins and and antibody, esp., between γ-Globulin and antibody; moreover, the fact that the function of reticuloendotherial system as springhead of antibody. Further, as a cause of individual difference in antibody formation, the amount of retained (possessed) normal γ-Globulin was considered significant.
Published Date
1957-05-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume69
Issue
issue5
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1311
End Page
1323
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/69/5/69_5_1311/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma