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ID 41154
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Title Alternative
Studies on Alkylphosphate Poisoning Part 2. Effect of Pyridine-2-aldoxime Methiodide (PAM) on Various Alkylphoshate Poisoning
Author
Uématsu, Yoshinori
Abstract
The author studied the effect of pyridine-2-aldoxime methiodide (PAM) on various alkylphosphate poisoning from the standpoints of (1) its effect on LD(50) in mice; (2) on the recovery of blood cholinesterase (ChE) in rabbits; and (3) on human cases. 1. The effectiveness of PAM against Ethyl- and Methyl- parathion was already established in human by Hiraki et al. The auther carried on animal experiments and ascertained the effectiveness. 2. In the cases of EPN and Diazinon poisoning PAM proves to be effective both in human and animals. 3. As for TEPP, Pestox-3, Malathon, Dipterex, and DFP, it was impossible to encounter human cases, but in animal experiments with these alkylphospnates PAM seems to be also effective. Therefore, PAM is to be applied for these alkylphosphate poisoning in human.
Published Date
1959-09-10
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue9-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
6111
End Page
6123
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/9-2/71_9-2_6111/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma