ID 32914
JaLCDOI
FullText URL
Author
Miyake, Yasuhiro
Iwasaki, Yoshiaki ORCID Kakenhi
Ishikawa, Shin
Tatsukawa, Masashi
Nawa, Toru
Kato, Jun
Takaki, Akinobu Kakenhi
Kobashi, Haruhiko
Sakaguchi, Kohsaku
Shiratori, Yasushi
Abstract
We report herein a case with acute hepatitis due to hepatitis B virus genotype Ae, concurrent with amebic colitis. A 39-year-old homosexual Japanese man was admitted to our hospital with jaundice. Laboratory tests showed an elevation of transaminase and positivity for hepatitis B surface antigen and IgM-type antibody to hepatitis B core antigen. The hepatitis B virus genotype was determined to be Ae. Furthermore, a mud-like stool with blood and mucous had sometimes been noted during the past 3 years, and amebic colitis was shown by colonofi berscopy during hospitalization. The patient was diagnosed with acute hepatitis B, concurrent with amebic colitis, and was successfully treated with lamivudine and metronidazole. In Japanese patients with acute hepatitis B virus genotype A infection, homosexual activity tends to be high. Furthermore, in Japanese homosexual men, amebiasis has been increasing. Thus, in Japanese patients with acute hepatitis B, a determination of genotype should be performed in order to investigate the route of transmission of hepatitis B virus, and a search for amebiasis should be performed in patients with acute hepatitis due to hepatitis B virus genotype A. Furthermore, education of homosexual men regarding hepatitis B virus, hepatitis B virus vaccination, and amebiasis is urgently required.
Keywords
hepatitis B virus
genotype
homosexual
amebic colitis
lamivudine
Amo Type
Case Report
Published Date
2007-02
Publication Title
Acta Medica Okayama
Volume
volume61
Issue
issue1
Publisher
Okayama University Medical School
Start Page
35
End Page
39
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Sience KeyUT