ID 32002
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Author
Nakanishi, Tohru
Akagi, Tadaatsu
Abstract

The structure of the human genome is almost completely elucidated and the life sciences will now aim for a general and integrated study of gene expressions and the functional elucidation of proteins. In such a study, various new techniques have been developed, and DNA microarray technology is the most representative one. As for the DNA microarray techniques, several thousands to tens of thousands of gene segments are immobilized on a glass slide at high density, and cDNA probes prepared from specific cells or tissues are hybridized on the slides from which gene expression profiles are obtained at one sweep in a short time. The present development of this technique and its possible application to medicine-related fields are described.</P>

Keywords
DNA microarray
DNA chip
human genome
embryonic stem(ES)cell
single nucleotide polymorphism(SNP)
Amo Type
Review
Published Date
2001-12
Publication Title
Acta Medica Okayama
Volume
volume55
Issue
issue6
Publisher
Okayama University Medical School
Start Page
319
End Page
328
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT