ID 30998
JaLCDOI
FullText URL
Author
Yamada, Teruo
Hirai, Yasuo
Sakano, Shigehiro
Kosaka, Makoto
Tada, Keiichi
Furutani, Sei
Kosaka, Futami
Abstract

The direct determination by gas chromatography of blood levels of anesthetic agents has been difficult because of the water content of blood. In the present study, the method of Yokota et al. (1967) was modified by improving the packing materials of the column, the blood sample vaporizer and the flow-path during analysis. As a result, accurate and reproducible determination of halothane, enflurane and isoflurane dissolved in blood was achieved. With this system, blood in which halothane, enflurane and isoflurane had been dissolved could be analyzed without changing the column between samples. Moreover, each sample was prepared in less than 10 min, and more than 100 consecutive determinations could be made with excellent reproducibility. The coefficient of variation was less than 3.8%.

Keywords
determination
halothane
enflurance
isoflurance
gas chromatography
Amo Type
Article
Published Date
1988-08
Publication Title
Acta Medica Okayama
Volume
volume42
Issue
issue4
Publisher
Okayama University Medical School
Start Page
183
End Page
192
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Sience KeyUT