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ID 19435
Eprint ID
19435
FullText URL
Thumnail 71_2127.pdf 336 KB
Title Alternative
Nitrogen Metabolism of the Brain Part 14 Influences Sodium Monofluoracetate on Ammonia, Glutamine and Amino Acids in the Rat Brain
Author
Ota, Tsuneko
Abstract
Administering the Sodium Monofluoracetate, SMFA, to the rat, the quantitative determination of ammonia and glutamine in the rat brain was made by the Conway's microdiffusion analysis and on the other hand amino acids by the paperchromatography. The results as follow, To wit: 1) In the convulsion stage caused by SMFA administration, ammonia content in its brain was 2.18 mg%, glutamine 63.9 m%, glutamic acid 120.7 mg%, γ-aminobutylic acid 25.2 mg% and aspartic acid 42.8 mg%. 2) About the hourly observation after the SMFA adiministration to the rat. a) Ammonia content in its brain showed gradual increase in 4 hours up to 4 times of control value. b) Glutamic acid content showed always low level in 4 hours but the lowest one in the first one hour. c) Glutamine content also decreased in all 4 hours, remarkably at the first and thlast. d) γ-amino butylic acid content decreased. e) Aspartic acid content increased remarkably in the first 10 minutes, and then decreased. But it showed remarkably increased at the 4th hour again.
Published Date
1959-04-15
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue5-1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2127
End Page
2132
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/5-1/71_5-1_2127/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma