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ID 18566
Eprint ID
18566
FullText URL
Thumnail 72_927.pdf 357 KB
Title Alternative
A Comparative Study on the Effect of Aureomycin, Chloromycetin, and Streptomycin on the Bacterial Respiration
Author
Kawai, Kiyoshi
Matsumoto, Toyozi
Honmatsu, Kakushi
Akiyama, Kengi
Abstract
This experiment was performed to investigate the effect of aureomycin, chloromycetin, and streptomycin upon the oxidation of several substrates by Sh. flexneri 2a and E. coli communis. The results are as follows: 1) A level of 200γ/ml aureomycin markedly inhibits the oxygen uptake with substrates such as glucose, pyruvate, glutamate, and aspartate. The inhibitory rate has no relation to the preincubation time of a mixture of aureomycin and a cell suspension. 2) A high concentration (200γ/ml) of chloromycetin slightly inhibits the oxidation of amino acids such as glutamate and aspartate. The inhibitory rate has a relation to the preincubation time of a mixture of chloromycetin and whole cell suspensions. 3) A level of 200γ/ml streptomycin slightly inhibits the oxidation of glutamate and aspartate by E. coli, but it does not affect the oxidation of glucose and pyruvate by this organism. The oxidation of proposed substrates by Sh. flexneri 2a is not also prevented by streptomycin. Even though streptomycin is added to the original cell suspension before the substrates and preincubated for an hour, the results are the same.
Published Date
1960-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume72
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
927
End Page
931
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/72/3/72_3_927/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma