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ID 18565
Eprint ID
18565
FullText URL
Thumnail 72_921.pdf 429 KB
Title Alternative
Studies on the Effect of Streptomycin on the Metabolic Activities of Bacteria
Author
Kawai, Kiyoshi
Matsumoto, Toyozi
Honmatsu, Kakushi
Abstract
This experiment was attempted to investigate the inhibitory action of streptomycin. The organism used is Shigella flexneri 2a. The results are as follows: 1) Even under a level of 200γ/ml streptomycin, it cannot inhibit the oxidation of pyruvate, succinate, fumarate, malate, glutamate, and aspartate by whole cell suspensions. 2) When glutamate is added to a cell suspension that has previously been permitted to oxidize fumarate, an immediate increase in oxygen consumption is observed. This increase is scarcely prevented by streptomycin. 3) The oxidatin of a mixture of glucose, glutamate, and 10(-3)M Mg(++) by a cell suspension is prevented by streptomycin level of 200γ/ml. 4) Streoptomycin prevents especially aerobic growth of this organism in the synthetic medium and results in an increased accumulation of pyruvate as a metabolic product.
Published Date
1960-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume72
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
921
End Page
926
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/72/3/72_3_921/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma