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ID 18354
Eprint ID
18354
FullText URL
Thumnail 77_1169.pdf 278 KB
Title Alternative
Experimental studies on the leukemogenesis in mice. Part 2. Effects of thymectomy and splenectomy on the incidence of leukemia by X-ray-irradiation in RF mice
Author
Kunisada, Mineo
Abstract
With the object to elucidate the role played by thymus and spleen in radiation leukemogenesis, effects of thymectomy and splenectomy on the induction of leukemia in RF mice by X-ray-irradiation were studied, dividing lymphocytic leukemia into thymic type and non-thymic type. As the result it has been clarified that thymectomy mainly inhibits the occurrence of the thymic type lymphocytic leukemia while splenectomy on the occurrence of the non-thymic type lymphocytic leukemia. As for the mechanism of this inhibition, a discussion was made on the significance of thymus and spleen as the organs that are constituted of the cells most susceptible to neoplastic transformation. After both thymectomy and splenectomy not a single mouse developed leukemia when exposed to X-ray-irradiation.
Published Date
1965-09-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume77
Issue
issue8-9
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1169
End Page
1173
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/77/8-9/77_8-9_1169/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma