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ID 17972
Eprint ID
17972
FullText URL
Thumnail 79_201.pdf 1.51 MB
Title Alternative
Studies on immunological role of the thymus Part 2. Experimental runt disease of mice by inoculation of the thymus cells
Author
Morita, Minoru
Abstract
1) The highest incidence of runt disease is obtained in case of thymus cell transplanted mice among cell graft experiments of various tissues of Db strain mice to R(Ⅲ)strain mice and those of R(Ⅲ)strain mice to Db strain mice. 2) The incidence is found to vary with the age of the donor mice from which thymus cells are supplied. The thymus cell of newborns has no ability to cause runt disease, but the incidence of the disease gradually increase after the age of 2 to 4 weeks of the donor mice. 3) Destruction and loss of lymphocytes are histologically demonstrated in the thymus of the thymus cell transplanted group. The same changes are observed in the spleen of the spleen cell transplanted group. 4) A marked increase of lymphoreticular cells were seen in the course of runt disease. 5) These findings suggest that the thymus of adult mice plays a significant role in immunological response of the body.
Published Date
1967-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume79
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
201
End Page
210
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/79/3-4/79_3-4_189/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma