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ID 17575
Eprint ID
17575
FullText URL
Thumnail 85_249.pdf 2.23 MB
Title Alternative
Studies on the induction and development of Iymphosarcoma by N-Nitrosobutylurea in RF Mice. Ⅰ. Histological and cytological observations
Author
Tanzi, Tameyo
Abstract
In order to study the carcinogenicity and its mechanism of N-Nitrosobutylurea (NBU), 10 week old RF mice was abministrated with 0.025% NBU water solution as drinking water every day. 1. Thymoma was induced after an average latency of 93 days and average rate of the tumor induction was 88.6%. Both sexes were equally susceptible. 2. Histologically thymoma was lymphosarcoma and other lymphatic organs also showed lymphosarcoma. However leukemic signs were not found in the peripheral blood and by clinical tissue culture. 3. Leukemia virus was not found in the electron microscpic observation and cell free transmission of leukemia was unsuccessfull.
Published Date
1973-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume85
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
249
End Page
264
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/85/7-8/85_7-8_249/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma