このエントリーをはてなブックマークに追加
ID 17280
Eprint ID
17280
FullText URL
Thumnail 90_461.pdf 5.15 MB
Title Alternative
Experimental and histochemical studies of the hippocampal formation
Author
Okano, Harumitsu
Abstract
The hippocamal formation of rat brain was studied by the silver sulfide method and was also observed by electron microscopy after the administration of dithizone, alloxan and oxine, respectively. In normal rat, the reaction products were found in the mossy fibers of granular cells of gyrus dentatus which ended to the dendrites of pyramydal cells present in h3, h4 and h5 area of the hippocampus. By electron microscopic observation, the mossy fiber endings of normal brain were filled with synaptic vesicles, and most of them ended to the dendritic spines of pyramidal cells. Zinc shown by silver sulfide method were not detected in the hippocampal formation from 1 to 3 hours after the administration of dithizone, and at the same time, the number of synaptic vesicles of the mossy fiber endings was decreased and the dendritic spines became to be smooth. Alloxan did not any effects of the amount of zinc and the number of synaptic vesicles in mossy fibers, while both of them decreased temporarily at 5 to 15 minutes after the administration of oxine. From these results, the correlation between zinc and synaptic vesicles in mossy fibers, and the mechanism of these drugs' action to zinc content and synaptic vesicles were discussed.
Published Date
1978-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume90
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
461
End Page
477
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/90/3-4/90_3-4_461/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma