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ID 17244
Eprint ID
17244
FullText URL
Thumnail 89_1475.pdf 4.38 MB
Title Alternative
Studies on the migration of basophilic leucocytes at the sites of allergic reactions Part III. Appearance of basophilic leucocytes at the sites of late and delayed skin reactions
Author
Abstract
The appearance of basophils and eosinophils at the sites of late or delayed skin reaction was examined in 34 bronchial asthmatics. Using guinea pigs, basophils at the site of cutaneous basophil hypersensitivity were observed with electron microscopy. The results were as follows. 1) The numbers of basophils and eosinophils increased significantly at the sites of positive delayed skin reaction to PPD and various allergens. Furthermore, the above phenomenon was much more conspicuous and significant at the sites of positive late reactions than of negative ones. 2) The appearance of basophils showed two peaks, i.e., at 30 minutes and 6 hours, after intradermal allergen injection. Eosinophils appeared at 6 hours in the peak. 3) In the cutaneous basophil hypersensitivity, migrating basophils and eosinophils were observed around the blood vessels in the hypodermis of guinea pigs. Electron microscopic observations demonstrated that basophils showed exocytotic degranulations were sometimes phagocytized by macrophages.
Published Date
1977-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume89
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1475
End Page
1485
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/89/11-12/89_11-12_1475/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma