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ID 17159
Eprint ID
17159
FullText URL
Thumnail 92_1115.pdf 317 KB
Title Alternative
Low molecular proteins in the urine of patients with systemic lupus erythematosus Part 2. Measurement of urinary β2-microglobulin
Author
Namba, Yoshio
Abstract
By the use of radioimmunoassay, urinary β2-microglobulin concentration was mesured in 49 patients with systemic lupus erythematosus (SLE). The urinary β2-microglobulin was significantly elevated in SLE (p<0.01). The level of urinary β2-microglobulin did not correlate with the level of serum complement, antibody to DNA or the massive proteinuria. It was associated with urinary free light chain and the degree of renal tubular damage, but not with the glomerular lesions observed in renal biopsy specimens. The elevated level of β2-microglobulin in urine was most likely due to increased excretion of β2-microglobulin from involved tubulus or direct secretion from lymphocytes infiltrating the interstitium. The measurement of the level of urinary β2-microglobulin is useful for estimating the extent of renal interstitial damage in patients with SLE.
Keywords
全身性エリテマトーデス
β2ミクログロブリン
Published Date
1980-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume92
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1115
End Page
1121
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/92/11-12/92_11-12_1115/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma