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ID 17013
Eprint ID
17013
FullText URL
Thumnail 91_1461.pdf 284 KB
Title Alternative
Experimental study of polychlorinated naphthalene (PCN) intoxication Report 2. Changes in oxidative phosphorylation of liver mitochondria, and in TBA and ATP of the liver.
Author
Ohoguma, Katsuaki
Abstract
PCN was dissolved in olive oil and given to rats intraperitoneally. The effect of PCN on liver mitochondria was compared with control rats given olive oil only. The results were as follows: The RCI of liver mitochondria had decreased significantly one hour after the injection of PCN. It was slightly decreased after 24 hours. The ADP/O ratio was slightly decreased one hour and 24 hours after the injection of PCN. The TBA value of the PCN injected group had increased significantly after 1 and 24 hours compared with the control, indicating that peroxidation of liver lipid had occurred. The level of ATP had decreased significantly compared with that of the control group 24 hours after the administration of PCN. Liver mitochondria showed greater uptake of components with shorter retention times than of those with longer retention times.
Keywords
ポリ塩化ナフタリン
酸化的リン酸化
脂質過酸化
ATP
Published Date
1979-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume91
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1461
End Page
1466
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/91/11-12/91_11-12_1461/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma