| ID | 16965 |
| Eprint ID | 16965
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| FullText URL | |
| Title Alternative | Changes in the DNA histogram and the amount of S-100 protein associated with morphological differentiation of cultured glioma cells.
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| Author |
Furuta, Tomohisa
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| Abstract | A flow cytometric analysis of DNA synthesis and a quantitative investigation of nervous system-specific S-100 protein were performed on cultured rat glioma (C-6) cells in the course of morphological differentiation induced by 1 mM dibutyryl cyclic AMP (dbc-AMP). The flow cytometric analysis revealed that a marked suppression of DNA synthesis was caused by dbc-AMP. The content of S-100 protein in dbc-AMP treated cells began to increase on the fourth day after the treatment with a subsequent increase to approximately 10-fold over the control cells at the stationary phase. These results suggest that S-100 protein is a useful biochemical index for estimating the degree of differentiation of glioma cells.
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| Keywords | 培養グリオーマ細胞
S-100蛋白
micro-complement fixation assay
flow cytometry
DNA ヒストグラム
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| Published Date | 1982-12-30
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| Publication Title |
岡山医学会雑誌
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| Publication Title Alternative | Journal of Okayama Medical Association
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| Volume | volume94
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| Issue | issue11-12
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| Publisher | 岡山医学会
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| Publisher Alternative | Okayama Medical Association
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| Start Page | 1113
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| End Page | 1125
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| ISSN | 0030-1558
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| NCID | AN00032489
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| Content Type |
Journal Article
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| Official Url | https://www.jstage.jst.go.jp/article/joma1947/94/11-12/94_11-12_1113/_article/-char/ja/
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| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
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| language |
日本語
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| Copyright Holders | 岡山医学会
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| File Version | publisher
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| Refereed |
True
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| Eprints Journal Name | joma
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