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ID 16954
Eprint ID
16954
FullText URL
94_1045.pdf 273 KB
Title Alternative
Studies on the biological toxicity of several hydrocarbon pollutants of the environment Report 2. The effect of halogenated hydrocarbons on oxidative phosphorylation and potassium compartmentalization of rat liver mitochondria.
Author
Ogino, Yasuo
Abstract
In order to investigate the influence of various environmental pollutants on living organisms, the effects of hlogenated hydrocarbons on the mitochondrial membrane were examined. The results obtained were as follows: 1) Monohalogenated benzenes decrease state 3 respiration and increase state 4 respiration, resulting in a decrease in both respiratory control (RCI) and the ADP/O ratio. 2) The above activity is in the decreasing order of iodobenzene, bromobenzene, chlorobenzene and fluorobenzene. This order of activity is parallel to that of potassium releasing activity. 3) Similarly to the effect of monohalogenated benzenes, brominated hydrocarbons also decrease both RCI and the ADP/O ratio. The activity is in the decreasing order of tribromobenzene, dibromobenzene, boron carbide, monobromobenzene and bromoform, which parallels the potassium releasing activity.
Keywords
ハロゲン化ベンゼン
ミトコンドリア
酸化的燐酸化
Published Date
1982-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume94
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1045
End Page
1050
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/94/11-12/94_11-12_1045/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma