このエントリーをはてなブックマークに追加
ID 16048
Eprint ID
16048
FullText URL
Thumnail 99_1461.pdf 1.43 MB
Title Alternative
Study of cell-mediated immunity in patients with brain tumor -Proportion of Tγ cells among peripheral lymphocytes-
Author
Fujiwara, Takashi
Abstract
Cell-mediated immunity was evaluated in 74 patients with brain tumor. The delayed type hypersensitivity skin test and the percentages of T and Tγ cells among peripheral lymphocyte were used as immunological parameters. Significant impairment of the delayed type hypersensitivity test and an increase in the Tγ cell counts were found in patients with malignant brain tumor as compared with normal controls and patients with benign tumor. After removal of the tumor, these parameters returned to normal. Tγ cell counts in patients with sub-tentorial tumor were significantly higher than those with supra-tentorial tumor. It has been suggested that certain intracranial tumors might interfere with the possible cerebral function participating in the regulation of cell mediated immunity. The Tγ cell level is considered to be a valuable parameter for evaluating cell mediated immunity in patients with malignant brain tumor.
Keywords
Brain tumor
Glioblastoma
Tγ cells
Delayed hypersensitivity reaction
Cell mediated immunity
Published Date
1987-12-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume99
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1461
End Page
1474
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/99/11-12/99_11-12_1461/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma