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ID 15890
Eprint ID
15890
FullText URL
Thumnail 99_311.pdf 421 KB
Title Alternative
Studies on gastric mucosal lesions in liver damage Part2 : A clinical study of patients with liver cirrhosis
Author
Sugihara, Toru
Abstract
In order to clarify the pathogenesis of gastric mucosal lesions in patients with liver cirrhosis(LC), gastric mucosal blood flow(BF), potential difference(PD) and prostaglandin E(2)(PGE(2)) of patients with LC were analyzed. Of 277 patients with LC, gastric ulcer or gastric erosions were observed in 178 patients (64.2%). The incidence of gastric mucosal lesions in patients with LC correlated with the degree of liver damage estmated by Child's classification. BF, PD and PGE(2) in patients with LC were lower than in control patients without liver disease. BF and PD decreased as the liver damage progressed. These results support the view that the impairment of the defensive factors of gastric mucosa represented by BF and PD play an important role in the pathogenesis of gastric mucosal lesions in patients with LC. PGE(2) was also implicated to be related to the pathogenesis of such lesions.
Keywords
肝硬変症
胃粘膜障害
胃粘膜血流
potential difference
Prostaglandin E(2)
Published Date
1987-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume99
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
311
End Page
320
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/99/3-4/99_3-4_311/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma