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ID 15090
Eprint ID
15090
FullText URL
Title Alternative
Gastro-biliary motility in patients with non-ulcer dyspepsia
Author
Yamamoto, Ryoichi
Matsumura, Naoki
Chowdhury, Riaz
Kato, Tadahiro
Ochi, Koji
Tanaka, Juntaro
Harada, Hideo
Yokota, Satoshi
Mifune, Takashi
Tanizaki, Yoshiro
Abstract
現在,上腹部不定愁訴の原因は特定されていない。その原因を解明するため,上腹部不定愁訴患者8人と健常対照者10人に対して液体食の胃排出能と,食事負荷による胆嚢収縮能を測定した。胃排出時間,胆嚢収縮能はいずれも両者に有意な差は認められなかった。健常対照者では胃排出時間と胆嚢収縮時間に有意な相関関係が認められたが,上腹部不定愁訴群では相関関係は認められなかった。上腹部不定愁訴の原因として胃・胆嚢協調運動障害の存在が示唆 された。
Abstract Alternative
Subjective symptoms are quite similar between cystic duct syndrome (CDS) and non-ulcer dyspepsia (NUD) : epigastralgia, hypochondralgia and vague complaints in the upper part of the abdomen. Recently, there has been several reports suggesting that the cause of these disorders is postprandial dysmotility in the gallbladder and stomach. However, there has been no report suggesting incoordination of postprandial gastrobilialy motility as the cause of tha above mentioned complaints in these disorders. The aim of this study was to define the difference of postprandial gastrobiliary motility between patients with NUD and controls. Eight patients with NUD and 10 controls were studied. Gastric emptying time of liquid meal and gallbladder contraction were measured, simultaneously. There was no significant difference between study patients and controls when gastric emptying time and gallbladder contraction rate were compared in isolation. However, when these two parameters were assessed in combination, gastric emptying time was linearly correlated with minimum ballbladder contraction time in controls but not in patients. We conclude that the incoordination between gastric emptying and minimal gallbladder contraction may be one of the major causes of the symptoms in NUD.
Keywords
胃運動 (Gastric motility)
胆嚢運動 (Biliary motility)
不定愁訴 (indefinite complaint)
Published Date
1996-11
Publication Title
岡大三朝分院研究報告
Publication Title Alternative
Annual Reports of Misasa Medical Branch, Okayama University Medical School
Volume
volume67
Publisher
岡山大学医学部附属病院三朝分院
Publisher Alternative
Misasa Medical Branch, Okayama University Medical School
Start Page
75
End Page
78
ISSN
0918-7839
NCID
AN10430852
Content Type
Departmental Bulletin Paper
language
日本語
File Version
publisher
Refereed
False
Eprints Journal Name
mmc