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ID 14043
Eprint ID
14043
FullText URL
106_443.pdf 4.52 MB
Title Alternative
Regional cerebral blood flow in Parkinson's disease by (123)I-IMP SPECT
Author
Kitamura, Yoshihiro
Abstract
Regional cerebral blood flow (rCBF) was evaluated in 63 patients with Parkinson's disease (PD) by single-photon emission computed tomography (SPECT) using N-isopropyl-p-(123)I-iodoamphetamine ((123)I-IMP) as a tracer. Evaluation of the SPECT images was performed in accordance with the rCBF quantification method using a microsphere model. Patients in stage Ⅳ demonstrated significanlty lower rCBF than those in stage Ⅱ at the frontal, tempo-ral, parietal, occipital regions and in the thalamus and celebellum. Subjects with mental sumptoms demonstrated decreased rCBF in every region in the brain. The present study indicates that clinical exacerbation and manifestation of dementia and other psychiatric aymptoms in Parkinson's disease are associated with decreased blood flow in various brain regions.
Keywords
Parkinson病
SPECT
臨床病期分類
精神症状
Note
原著
Published Date
1994
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume106
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
443
End Page
450
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/106/5-6/106_5-6_443/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma