このエントリーをはてなブックマークに追加
ID 13216
Eprint ID
13216
FullText URL
Thumnail 119_235.pdf 440 KB
Title Alternative
Quinone formation as a common neurotoxic factor in dopaminergic neurotoxicity induced by an excess amount of cytosolic dopamine
Author
Francisco J. Diaz-Corrales
Ogawa, Norio
Keywords
ドパミンキノン
パーキンソン病
メタンフェタミン
キノン還元酵素
チロシナーゼ
Note
平成18年度岡山医学会賞(新見賞)受賞論文
Published Date
2008-01-04
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume119
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
235
End Page
239
ISSN
00301558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/
References
1) Asanuma M, Miyazaki I and Ogawa N : Dopamine- or L-DOPA-induced neurotoxicity : the role of dopamine quinone formation and tyrosinase in a model of Parkinson's disease. Neurotox Res (2003) 5, 165-176.
2) Sulzer D, Bogulavsky J, Larsen KE, Behr G, Karatekin E, Kleinman MH, Turro N, Krantz D, Edwards RH, Greene LA and Zecca L : Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles. Proc Natl Acad Sci USA (2000) 97, 11869-11874.
3) Whitehead RE, Ferrer JV, Javitch JA and Justice JB : Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter. J Neurochem (2001) 76, 1242-1251.
4) Kuhn DM, Arthur RE Jr, Thomas DM and Elferink LA : Tyrosine hydroxylase is inactivated by catechol-quinones and converted to a redox-cycling quinoprotein : possible relevance to Parkinson's disease. J Neurochem (1999) 73, 1309-1317.
5) LaVoie MJ, Ostaszewski BL, Weihofen A, Schlossmacher MG and Selkoe DJ : Dopamine covalently modifies and functionally inactivates parkin. Nat Med (2005) 11, 1214-1221.
6) Cadet JL and Brannock C : Free radicals and the pathobiology of brain dopamine systems. Neurochem Int (1998) 32, 117-131.
7) Miyazaki I, Asanuma M, Diaz-Corrales FJ, Fukuda M, Kitaichi K, Miyoshi K and Ogawa N : Methamphetamine-induced dopaminergic neurotoxicity is regulated by quinone formation-related molecules. FASEB J (2006) 20, 571-573.
8) Ogawa N, Tanaka K and Asanuma M : Bromocriptine markedly suppresses levodopa-induced abnormal increase of dopamine turnover in the parkinsonian striatum. Neurochem Res (2000) 25, 755-758.
9) Miyazaki I, Asanuma M, Diaz-Corrales FJ, Miyoshi K and Ogawa N : Dopamine agonist pergolide prevents levodopa-induced quinoprotein formation in parkinsonian striatum and shows quenching effects on dopamine-semiquinone generated in vitro. Clin Neuropharmcol (2005) 28, 155-160.
10) Haque ME, Asanuma M, Higashi Y, Miyazaki I, Tanaka K and Ogawa N : Apoptosis-inducing neurotoxicity of dopamine and its metabolites via reactive quinone generation in neuroblastoma cells. Biochim Biophys Acta (2003) 1619, 39-52.
11) LaVoie MJ and Hastings TG : Peroxynitrite- and nitrite-induced oxidation of dopamine : implications for nitric oxide in dopaminergic cell loss. J Neurochem (1999) 73, 2546-2554.
12) Offen D, Ziv I, Sternin H, Melamed E and Hochman A : Prevention of dopamine-induced cell death by thiol antioxidants : possible implications for treatment of Parkinson's disease. Exp Neurol (1996) 141, 32-39.
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
DOI
Eprints Journal Name
joma