ID | 14544 |
Eprint ID | 14544
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FullText URL | |
Title Alternative | Clinical studies on serum factors in patients with bronchal asthma Part 1. Changes in α(1)-Antitrypsin and α(1)-Acid glycoprotein levels in patients with bronchial asthma and other respiratory diseases
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Author |
Ishibashi, Ken
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Abstract | Serum α(1)-Antitrypsin (α(1)-AT) and α(1)-Acid glycoprotein (α(1)-AG) levels were measured in 34 healthy subjects, 167 patients with bronchial asthma and 82 cases with other respiratory diseases. The serum levels of α(1)-AT were significantly increased in patients over 40 years old and the levels of α(1)-AG were significantly higher in patients over 50 years old compared to the those under 50 years old.
The serum levels of α(1)-AT and α(1)-AG were significantly more increased in asthmatic patients with mixed and infective type during asymptomatic periods than in healthy subjects.
The levels of α(1)-AT were significantly higher in patients with mild and moderate asthma than in healthy subjects. The levels of α(1)-AG were also significantly higher in mild and severe asthmatic patients than in healthy subjects.
Patients with severe asthma showed more increased levels of α(1)-AT during attack periods compared to that during non-attack periods. The levels of α(1)-AT and α(1)-AG in asthma patients with steroid therapy were within normal limits during the non-attack periods, but significantly increased during the attack periods. In asthmatic patients with mixed type, infectious type, severe type and steroid therapy, a correlation was observed between the serum levels of α(1)-AT and α(1)-AG during their attack periods.
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Keywords | 気管支喘息
α(1)-Antitrypsin
α(1)-Acid glycoprotein
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Note | 原著
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Published Date | 1991
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume103
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Issue | issue4
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 419
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End Page | 434
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ISSN | 0030-1558
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NCID | AN00032489
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Content Type |
Journal Article
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Official Url | https://www.jstage.jst.go.jp/article/joma1947/103/4/103_4_419/_article/-char/ja/
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Related Url | http://www.okayama-u.ac.jp/user/oma/
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language |
Japanese
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Copyright Holders | 岡山医学会
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File Version | publisher
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Refereed |
True
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Eprints Journal Name | joma
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